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‘Punjabis more prone to heart attacks’

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Express news service

Posted: Feb 25, 2008 at 2115 hrs IST

Amritsar, February 24 Punjabi population is more prone to heart diseases due to the low presence of para-oxonase-I enzyme, a component of HDL molecule, which is the good cholesterol.

This disheartening news was broken today on the concluding day of the two-day-long international medical conference, organised by Amritsar Medical College Alumni Association (AMCAA) jointly with Amritsar Medical and Dental Alumni Association of North America (AMDAANA) here.

The research paper, read by Dr Ritu Sharma from the Department of Bio-chemistry, Government Medical College, revealed that in a survey conducted on 522 coronary artery disease patients and 300 normal individuals, it was found that the low activity of the enzyme was leading to the hardening of the arteries.

“The enzyme’s shortage, due to genetic reasons, is responsible for the low anti-oxidant potential of HDL and more production of oxidised LDL, leading to hardening of arteries, the major reason for heart attacks,” said Dr Sharma, who was assisted in the research by her guide and Prof Mridula Mahajan, Dr Kavi Kant, CMO-cum-Medical Superintendent ESI Hospital and Dr Balwant Singh, Head Department of Molecular Biology, GNDU.

The alumni of the college, including Prof Satwant Singh from Cincinnati, USA, Dr Ved Gosain from Michigan University and others, said they would help researchers from their alma mater to get their papers published in the reputed international magazines.

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