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The blast occurred shortly before 7 pm when a large congregation was present outside the imambargah or prayer hall, TV channels said.
At least three persons were killed, Geo News reported.
There was no official word on the casualties. Rescue workers and police rushed to the site and ferried the injured and bodies to nearby hospitals.
The imambargah is located in a thickly populated part of Dera Ghazi Khan.
No group claimed responsibility for the attack. It was also not immediately clear if the blast was caused by an explosive device or a suicide bomber.


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