www.expressindia.com - Weather | Horoscope | Stocks | RSS
expressindia web city
HomeBlogsCricketAstrology TendersClassifieds Reader Comments Hotels
Sign In / Register | Archive
Expressindia » Story

Domino effect: Two toddlers cured with one donor liver

Font Size

Express News Service

Posted: Feb 20, 2009 at 0056 hrs IST

New Delhi Two children from the city, Shaurya, 22 months, and two-year-old Siya, have become the world’s youngest and the country’s first beneficiaries of an organ transplant procedure known as the ‘domino’ or sequential liver transplant.

This unique procedure involved one single donor liver. Shaurya’s aunt Mukta donated 20 per cent of her liver to Shaurya to cure a rare condition Shaurya was battling — the Maple Syrup Urine Disorder or MSUD.

His liver was then transplanted into Siya, who is undergoing treatment for terminal liver failure. Her condition is known as Langerhan’s Cell Histiocytosis (LCH).

Due to this procedure, Shaurya has been cured of MSUD, while things are looking better for Siya. The operations, at one go, took 16 hours on January 31. Twenty surgeons performed the marathon surgeries at the Sir Ganga Ram Hospital, the first in the country to perform a ‘domino’ transplant. All three are doing well and have been discharged.

Shaurya’s condition was from birth. MSUD is caused when there is a build-up of amino acids in the body due to an absent enzyme.

The high level of acids in urine makes it smell like sugar and hence the name Maple Syrup Urine Disease. Shaurya’s father Prashant Verma said: “He needed a specialised diet, devoid of amino acids. But the diet would have only shrunk as he grew older — therefore, the operation.”

Siya’s condition affects multiple organs and leads to liver failure. Her mother Swati Thakur said: “She was on chemotherapy, but the disease continued to spread. Her liver was irreversibly damaged.”

Chief surgeon of liver transplants at the hospital, Dr A S Soin, said they were in touch with medical centres abroad which had been successful in sequential transplant. “We wanted to be absolutely sure and hence consulted centres in Pittsburgh. We also checked with them the age of former liver recipients. The youngest till now had been eight. ‘Domino’ transplants are rare because there are very few conditions in which you can conduct sequential transplant without passing on the disease to the donor who receives the full organ. In this case, MSUD happens to be among those diseases which does not pass on.”

According to doctors, this procedure has made Shaurya the country’s first and the world’s youngest recipient of a living donor liver transplant for MSUD. Siya is also the country’s first and the world’s youngest participant in the ‘domino’ liver transplant.

Chief paediatric hepatologist Neelam Mohan also ruled out any future complications. She said: “They will be normal in three months. “We shall keep an eye on them to check if the disease relapses,” she added.

Discuss this story on expressindia forums
Post Comments
Name* Email ID*
Subject* Country*
Message*
Characters remaining
 
TERMS OF USE: The views, opinions and comments posted are your, and are not endorsed by this website. You shall be solely responsible for the comment posted here. The website reserves the right to delete, reject, or otherwise remove any views, opinions and comments posted or part thereof. You shall ensure that the comment is not inflammatory, abusive, derogatory, defamatory &/or obscene, or contain pornographic matter and/or does not constitute hate mail, or violate privacy of any person (s) or breach confidentiality or otherwise is illegal, immoral or contrary to public policy. Nor should it contain anything infringing copyright &/or intellectual property rights of any person(s).
I agree to the terms of use.

Latest News

Business

Showbiz

Sports

Now, plan for OBC quota in petrol pump allotment

NRHM scam: CBI probe reaches Sports Ministry centre

Public perception UPA-2 will crumble, says Pawar

Abandoned passports help Customs uncover human trafficking racket

Sub-quota remark part of pre-declared policy: Khurshid

Took outsiders as didn’t have good candidates: Digvijaya

In team Anna Pamphlet, 'central govt's fraud'

More
© 2011 The Indian Express Limited. All rights reserved
Advertise With Us | Privacy Policy | Feedback | Express Group | Site Map